J Biomed 2017; 2:120-123. doi:10.7150/jbm.20986 This volume


The Endothelial Glycocalyx: Visualization and Measurement

Hongyan Kang, Xiaoyan Deng

Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China.

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Kang H, Deng X. The Endothelial Glycocalyx: Visualization and Measurement. J Biomed 2017; 2:120-123. doi:10.7150/jbm.20986. Available from /v02p0120.htm

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Graphic abstract

The endothelial glycocalyx is a hair-like surface layer mainly consisted of glycosaminoglycans (GAGs) that includes heparan sulfate (HS), chondroitin sulfate (CS), and hyaluronic acid (HA) and its bearing core proteins (syndecan, glypican, and perlecan). This mini review presents the visualization and measurement techniques of the endothelial glycocalyx up to now, providing insight to the diagnosis, treatment, and protection of the cardiovascular disease.

Keywords: Glycocalyx, transmission electron microscopy, intravital microscopy, confocal laser scanning microscopy, two-photon laser scanning microscopy.