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Volume 16 (14); 2020

Research Papers

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S-Palmitoylation as a Functional Regulator of Proteins Associated with Cisplatin Resistance in Bladder Cancer
Muhammad Shahid, Minhyung Kim, Peng Jin, Bo Zhou, Yang Wang, Wei Yang, Sungyong You, Jayoung Kim
Int. J. Biol. Sci. 2020; 16(14): 2490-2505. doi:10.7150/ijbs.45640
[Abstract] [Full text] [PDF]


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Highly bioavailable Berberine formulation improves Glucocorticoid Receptor-mediated Insulin Resistance via reduction in association of the Glucocorticoid Receptor with phosphatidylinositol-3-kinase
Zhaojie Meng, Yang Yu, Yining Zhang, Xuehan Yang, Xiaoyan Lv, Fengying Guan, Grant M. Hatch, Ming Zhang, Li Chen
Int. J. Biol. Sci. 2020; 16(14): 2527-2541. doi:10.7150/ijbs.39508
[Abstract] [Full text] [PDF]


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Cancer-associated Fibroblasts induce epithelial-mesenchymal transition via the Transglutaminase 2-dependent IL-6/IL6R/STAT3 axis in Hepatocellular Carcinoma
Changchang Jia, Guoying Wang, Tiantian Wang, Binsheng Fu, Yincai Zhang, Lei Huang, Yinan Deng, Guanzhong Chen, Xiaocai Wu, Jianning Chen, Yuhang Pan, Yan Tai, Jinliang Liang, Xuejiao Li, Kunhua Hu, Bo Xie, Sujun Li, Yang Yang, Guihua Chen, Qi Zhang, Wei Liu
Int. J. Biol. Sci. 2020; 16(14): 2542-2558. doi:10.7150/ijbs.45446
[Abstract] [Full text] [PDF]


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Metformin suppresses inflammation and apoptosis of myocardiocytes by inhibiting autophagy in a model of ischemia-reperfusion injury
Kai-yu Huang, Jia-qun Que, Ze-song Hu, Yong-wei Yu, Ying-ying Zhou, Lei Wang, Yang-jing Xue, Kang-ting Ji, Xin-min Zhang
Int. J. Biol. Sci. 2020; 16(14): 2559-2579. doi:10.7150/ijbs.40823
[Abstract] [Full text] [PDF]


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Cancer stem cell property and gene signature in bone-metastatic Breast Cancer cells
An Luo, Yue Xu, Shujun Li, Jinxia Bao, Jinhui Lü, Nan Ding, Qian Zhao, Yuting Fu, Fei Liu, William C. Cho, Xunbin Wei, Haiyun Wang, Zuoren Yu
Int. J. Biol. Sci. 2020; 16(14): 2580-2594. doi:10.7150/ijbs.45693
[Abstract] [Full text] [PDF]


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Chidamide increases the sensitivity of Non-small Cell Lung Cancer to Crizotinib by decreasing c-MET mRNA methylation
Nan Ding, Abin You, Wei Tian, Liankun Gu, Dajun Deng
Int. J. Biol. Sci. 2020; 16(14): 2595-2611. doi:10.7150/ijbs.45886
[Abstract] [Full text] [PDF]


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MiR-216a-5p inhibits tumorigenesis in Pancreatic Cancer by targeting TPT1/mTORC1 and is mediated by LINC01133
Jian Zhang, Shuohui Gao, Yandong Zhang, Huixin Yi, Mengxian Xu, Jialun Xu, HuanLiu, Zhichen Ding, Hongbin He, Hongmei Wang, Zhuo Hao, Liankun Sun, Yan Liu, Feng Wei
Int. J. Biol. Sci. 2020; 16(14): 2612-2627. doi:10.7150/ijbs.46822
[Abstract] [Full text] [PDF]


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Jagged2 progressively increased expression from Stage I to III of Bladder Cancer and Melatonin-mediated downregulation of Notch/Jagged2 suppresses the Bladder Tumorigenesis via inhibiting PI3K/AKT/mTOR/MMPs signaling
Yen-Ta Chen, Chi-Ruei Huang, Chia-Lo Chang, John Y. Chiang, Chi-Wen Luo, Hong-Hwa Chen, Hon-Kan Yip
Int. J. Biol. Sci. 2020; 16(14): 2648-2662. doi:10.7150/ijbs.48358
[Abstract] [Full text] [PDF]


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Encoding Method of Single-cell Spatial Transcriptomics Sequencing
Ying Zhou, Erteng Jia, Min Pan, Xiangwei Zhao, Qinyu Ge
Int. J. Biol. Sci. 2020; 16(14): 2663-2674. doi:10.7150/ijbs.43887
[Abstract] [Full text] [PDF]


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The role of monoamine oxidase A in HPV-16 E7-induced epithelial-mesenchymal transition and HIF-1α protein accumulation in non-small cell lung cancer cells
Bingyu Huang, Zhiyuan Zhou, Jiao Liu, Xin Wu, Xiangyong Li, Qiang He, Peihua Zhang, Xudong Tang
Int. J. Biol. Sci. 2020; 16(14): 2692-2703. doi:10.7150/ijbs.46966
[Abstract] [Full text] [PDF]

Reviews

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Immune Response and COVID-19: A mirror image of Sepsis
Eduardo López-Collazo, José Avendaño-Ortiz, Alejandro Martín-Quirós, Luis A. Aguirre
Int. J. Biol. Sci. 2020; 16(14): 2479-2489. doi:10.7150/ijbs.48400
[Abstract] [Full text] [PDF]


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Insights into Nanomedicine for Immunotherapeutics in Squamous Cell Carcinoma of the head and neck
Qiang Xu, Meiyu Fang, Jing Zhu, Haoru Dong, Jun Cao, Lin Yan, Fransisca Leonard, Felix Oppel, Holger Sudhoff, Andreas M. Kaufmann, Andreas E. Albers, Xu Qian
Int. J. Biol. Sci. 2020; 16(14): 2506-2517. doi:10.7150/ijbs.47068
[Abstract] [Full text] [PDF]


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Immunoproteasome in IgA Nephropathy: State-of-Art and Future Perspectives
Ting Gan, Yang Li, Xu-jie Zhou, Hong Zhang
Int. J. Biol. Sci. 2020; 16(14): 2518-2526. doi:10.7150/ijbs.48330
[Abstract] [Full text] [PDF]


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miRNA-based biomarkers, therapies, and resistance in Cancer
Boxue He, Zhenyu Zhao, Qidong Cai, Yuqian Zhang, Pengfei Zhang, Shuai Shi, Hui Xie, Xiong Peng, Wei Yin, Yongguang Tao, Xiang Wang
Int. J. Biol. Sci. 2020; 16(14): 2628-2647. doi:10.7150/ijbs.47203
[Abstract] [Full text] [PDF]


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The Role of Autophagy and Mitophagy in Bone Metabolic Disorders
Shuai Wang, Zhantao Deng, Yuanchen Ma, Jiewen Jin, Fangjie Qi, Shuxian Li, Chang Liu, Feng-Juan Lyu, Qiujian Zheng
Int. J. Biol. Sci. 2020; 16(14): 2675-2691. doi:10.7150/ijbs.46627
[Abstract] [Full text] [PDF]